Month: October 2024

SOP for Preparation of Nanoparticles for Sublingual Administration

SOP for Preparation of Nanoparticles for Sublingual Administration Standard Operating Procedure for Preparation of Nanoparticles for Sublingual Administration 1) Purpose This SOP outlines the procedure for preparing nanoparticles for sublingual drug delivery, allowing for rapid absorption of drugs through the mucosal tissues under the tongue, bypassing first-pass metabolism and providing faster therapeutic effects. 2) Scope…

Nanoparticle Formulation

SOP for Use and Calibration of Weighing Balances

SOP for Use and Calibration of Weighing Balances Standard Operating Procedure for Use and Calibration of Weighing Balances 1) Purpose The purpose of this SOP is to provide instructions for the proper use and calibration of weighing balances used for measuring ingredients in nasal formulations. Regular calibration ensures accurate weight measurements for ingredient consistency. 2)…

Nasal Spray Formulations

SOP for High-Shear Mixing in Emulsion Preparation

SOP for High-Shear Mixing in Emulsion Preparation High-Shear Mixing in Emulsion Preparation 1) Purpose The purpose of this SOP is to describe the procedure for using high-shear mixing to prepare emulsions. High-shear mixing ensures the formation of stable emulsions by reducing droplet size and providing uniform mixing. This technique is commonly employed to prepare emulsions…

Liposome and Emulsion Formulations

SOP for Cleaning and Maintenance of Lyophilizer Equipment

SOP for Cleaning and Maintenance of Lyophilizer Equipment Standard Operating Procedure for Cleaning and Maintenance of Lyophilizer Equipment 1) Purpose This SOP outlines the procedure for the routine cleaning and maintenance of lyophilizer equipment to ensure optimal performance, prevent contamination, and extend equipment life. 2) Scope This SOP applies to maintenance personnel, operators, and QA…

Lyophilized Products

SOP for Incorporation of Bioactive Molecules in Nanoparticle-Based Formulations

SOP for Incorporation of Bioactive Molecules in Nanoparticle-Based Formulations Standard Operating Procedure for Incorporation of Bioactive Molecules in Nanoparticle-Based Formulations 1) Purpose This SOP outlines the procedure for incorporating bioactive molecules, such as proteins, peptides, or small molecules, into nanoparticle formulations for targeted drug delivery or therapeutic applications. 2) Scope This SOP applies to personnel…

Nanoparticle Formulation

SOP for Setup and Calibration of Lyophilizer Equipment

SOP for Setup and Calibration of Lyophilizer Equipment Standard Operating Procedure for Setup and Calibration of Lyophilizer Equipment 1) Purpose This SOP outlines the procedure for setting up and calibrating lyophilizer equipment to ensure that all lyophilization cycles are conducted accurately and consistently. 2) Scope This SOP applies to all maintenance personnel, operators, and QA…

Lyophilized Products

SOP for Operation of Spray Dryers for Nasal Powders

SOP for Operation of Spray Dryers for Nasal Powders Standard Operating Procedure for Operation of Spray Dryers for Nasal Powders 1) Purpose This SOP outlines the procedures for operating spray dryers to produce nasal powder formulations. The spray drying process helps achieve consistent particle size and moisture content for nasal powder delivery systems. 2) Scope…

Nasal Spray Formulations

SOP for Formulating Self-Emulsifying Drug Delivery Systems (SEDDS)

SOP for Formulating Self-Emulsifying Drug Delivery Systems (SEDDS) Formulating Self-Emulsifying Drug Delivery Systems (SEDDS) 1) Purpose This SOP outlines the procedure for formulating Self-Emulsifying Drug Delivery Systems (SEDDS), which are lipid-based formulations designed to improve the bioavailability of poorly water-soluble drugs. SEDDS formulations spontaneously emulsify into fine oil-in-water emulsions when exposed to gastrointestinal fluids, enhancing…

Liposome and Emulsion Formulations

SOP for Preparation of Inorganic Nanoparticles

SOP for Preparation of Inorganic Nanoparticles Standard Operating Procedure for Preparation of Inorganic Nanoparticles 1) Purpose This SOP outlines the procedure for the preparation of inorganic nanoparticles, such as gold, silver, and zinc oxide nanoparticles, which are used in various biomedical, industrial, and environmental applications. 2) Scope This SOP applies to laboratory personnel responsible for…

Nanoparticle Formulation

SOP for Lyophilization of Live Attenuated Vaccines

SOP for Lyophilization of Live Attenuated Vaccines Standard Operating Procedure for Lyophilization of Live Attenuated Vaccines 1) Purpose This SOP outlines the procedure for lyophilizing live attenuated vaccines to ensure the stability and viability of the vaccine during storage and transport. 2) Scope This SOP applies to all personnel involved in the formulation, preparation, and…

Lyophilized Products