Standard Operating Procedure for Equipment Shutdown and Restart Procedures

1) Purpose

The purpose of this SOP is to establish procedures for the safe and efficient shutdown and restart of equipment used in the manufacturing of dental dosage forms to prevent damage and ensure operational readiness.

2) Scope

This SOP applies to all equipment used in the production of dental pastes, gels, and mouthwashes within the pharmaceutical industry.

3) Responsibilities

The Production Department is responsible for executing equipment shutdown and restart procedures. The Maintenance Department is responsible for verifying equipment condition and readiness.

4) Procedure

4.1 Shutdown Procedures

4.1.1 Notify all relevant personnel about the intention to shut down the equipment.

4.1.2 Follow equipment-specific shutdown procedures provided by the manufacturer.

4.1.3 Ensure all product materials are properly disposed of or stored according to procedure.

4.2 Equipment Inspection and Preparation

4.2.1 Inspect equipment for any abnormalities or signs of wear and tear.

4.2.2 Perform necessary cleaning and sanitization of equipment parts as per standard operating procedures.

4.3 Restart Procedures

4.3.1 Ensure all maintenance and cleaning activities are completed and documented.

4.3.2 Follow manufacturer’s recommended procedures for equipment startup.

4.3.3 Conduct functional checks and verify equipment readiness for production.

4.4 Safety Checks

4.4.1 Verify safety features such as emergency stops and alarms are functional.

4.4.2 Conduct operational checks