SOPs for Drug Discovery

The purpose of this Standard Operating Procedure (SOP) is to define the process for using predictive tools in formulation development. Predictive tools are computational methods and models that are used to forecast the behavior of drug formulations under various conditions. These tools can help optimize formulation strategies, reduce the need for extensive experimental work, and accelerate the development of new drug products. This SOP provides guidelines for the selection, implementation, and validation of predictive tools in the formulation development process.
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The purpose of this Standard Operating Procedure (SOP) is to define the procedure for testing the compatibility of pharmaceutical formulations with packaging materials. The choice of packaging material is critical to the stability, safety, and quality of the drug product. This SOP provides guidelines for assessing the interaction between the drug product and packaging materials to ensure that the packaging does not affect the product’s stability, efficacy, or safety over its shelf life.
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The purpose of this Standard Operating Procedure (SOP) is to define the procedure for screening film-coating formulations used in pharmaceutical tablet manufacturing. Film-coating is an essential process for improving tablet stability, appearance, and controlled drug release. This SOP provides guidelines for selecting and evaluating film-coating formulations, including excipient selection, preparation, testing, and optimization to ensure the best performance of the coated tablets.
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The purpose of this Standard Operating Procedure (SOP) is to define the procedure for screening tablet formulations during pharmaceutical development. Tablet formulations must meet specific criteria to ensure their stability, bioavailability, and manufacturing suitability. This SOP provides guidelines for the preparation, characterization, and optimization of tablet formulations, with a focus on excipient selection, drug release, and tablet quality attributes.
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The purpose of this Standard Operating Procedure (SOP) is to establish the process for screening formulations intended for injectable delivery. Injectable formulations must meet stringent criteria for safety, stability, solubility, and sterility, among other factors. This SOP provides guidelines for evaluating different formulation types, such as solutions, suspensions, and emulsions, for their suitability as injectable drug delivery systems.
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The purpose of this Standard Operating Procedure (SOP) is to define the process for selecting surfactants during formulation development. Surfactants are essential in the preparation of emulsions, suspensions, solid dispersions, and other drug delivery systems. The selection of an appropriate surfactant is critical to the stability, bioavailability, and overall performance of the final formulation. This SOP provides guidelines for choosing the right surfactant based on its properties, compatibility with the drug, and the desired formulation characteristics.
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The purpose of this Standard Operating Procedure (SOP) is to define the procedure for screening emulsion formulations in pharmaceutical development. Emulsions are widely used for the delivery of hydrophobic drugs in a stable, bioavailable form. This SOP provides guidelines for preparing, testing, and optimizing emulsions for solubility enhancement, stability, and drug release properties.
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The purpose of this Standard Operating Procedure (SOP) is to establish the procedure for screening drug nanoparticles aimed at enhancing the solubility of poorly water-soluble drugs. Nanoparticles can significantly improve the solubility and bioavailability of drugs that are hydrophobic or poorly soluble in aqueous media. This SOP outlines the preparation, characterization, solubility testing, and selection of the most effective nanoparticle formulation for solubility enhancement.
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The purpose of this Standard Operating Procedure (SOP) is to outline the process for screening lipid-based formulations used to enhance the solubility and bioavailability of poorly water-soluble drugs. Lipid-based formulations, such as lipid emulsions, liposomes, and self-emulsifying drug delivery systems (SEDDS), are critical in improving the dissolution rates and overall therapeutic efficacy of hydrophobic drug molecules. This SOP provides guidelines for preparing, evaluating, and selecting optimal lipid formulations.
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The purpose of this Standard Operating Procedure (SOP) is to define the procedure for screening lipid-based formulations for the delivery of poorly water-soluble drugs. Lipid-based formulations, such as liposomes, solid lipid nanoparticles (SLNs), and self-emulsifying drug delivery systems (SEDDS), are widely used to improve the solubility, bioavailability, and therapeutic efficacy of hydrophobic drugs. This SOP outlines the necessary steps for preparing lipid-based formulations, testing for solubility enhancement, and evaluating the physicochemical properties of the formulations.
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