Job Safety Analysis for Double Cone Blender

JSA for Safe Operation of Double Cone Blender

JSA Number	JSA/OralDosage/009/2025	Department	Oral Dosage
Revision Number	V 1.0	Issue Date	01/02/2025
Effective Date	05/02/2025	Review Date	05/02/2026

1. Purpose

The purpose of this JSA is to identify and mitigate potential hazards associated with the operation of the Double Cone Blender. This machine is widely used in the pharmaceutical industry for blending dry powders and granules uniformly to produce oral solid dosage forms. The efficient operation of the Double Cone Blender ensures the proper mixing of materials, preventing formulation inconsistencies and quality deviations.

2. Scope

This JSA applies to all operators, maintenance personnel, and supervisors involved in the operation, cleaning, and maintenance of the Double Cone Blender. Proper safety measures are essential to avoid physical injuries, contamination risks, and mechanical failures.

3. Responsibilities

Operators:

Follow the standard operating procedure (SOP) for the Double Cone Blender.
Wear appropriate Personal Protective Equipment (PPE) before starting operations.
Ensure materials are properly loaded into the blender.
Monitor machine performance and report any malfunctions.
Clean the blender thoroughly after each batch to prevent cross-contamination.

Supervisors:

Ensure strict compliance with safety protocols and monitor daily operations.
Conduct routine inspections and ensure all safety measures are followed.
Provide training to operators on safe handling and emergency procedures.

Safety Officers:

Conduct routine safety inspections and audits.
Ensure

that all operators are trained in emergency response procedures.

Implement risk assessment measures to reduce potential hazards.

4. Definitions & Abbreviations

PPE: Personal Protective Equipment (e.g., gloves, goggles, respirators).
LOTO: Lockout/Tagout – Procedure for safely isolating hazardous energy sources.
Risk Assessment: Process of identifying and mitigating hazards.

5. Procedure

Step	Task Description	Potential Hazard	Risk Level (L/M/H)	Control Measures
1	Machine setup and calibration	Pinching, crushing injuries due to moving parts	High	Ensure guards are in place; follow SOP before making adjustments.
2	Loading raw materials	Ergonomic strain, dust inhalation, spillage	Medium	Use lifting aids; wear respiratory protection; use spill control measures.
3	Blending operation	Entanglement in rotating parts, noise exposure	High	Ensure hands are clear of rotating parts; use ear protection.
4	Unloading blended material	Cross-contamination, repetitive strain injury	Medium	Ensure proper cleaning between batches; use ergonomic lifting techniques.
5	Cleaning and maintenance	Exposure to cleaning chemicals, electrical hazards	High	Wear gloves and goggles; follow LOTO procedures before maintenance.

6. Risk Assessment

Likelihood	Consequence	Risk Level
Rare	Minor injuries (cuts, bruises)	Low
Possible	Strain injuries due to manual handling	Medium
Likely	Serious injury from mechanical failure	High

7. Emergency Procedures

If an injury occurs, seek medical assistance immediately.
For mechanical failures, shut down the machine and inform maintenance.
In case of inhalation of powders, move to fresh air and seek medical help.
All incidents must be recorded in the safety logbook.

8. Required PPE & Safety Controls

Safety gloves: Prevent cuts and abrasions during operation.
Respiratory mask: Reduces exposure to airborne powder particles.
Hearing protection: Required in high-noise areas.
Face shield: Protects from accidental powder splashes.
Machine guard: Must be in place before operation.

9. References

OSHA 1910.212 – Machine Guarding Standards.
ISO 45001 – Occupational Health & Safety Standards.
Manufacturer’s Operation Manual for Double Cone Blender.

10. Approval Section

Name	Designation	Signature	Date
[Name]	Prepared By
[Name]	Checked By
[Name]	Approved By

11. Revision History

Version	Date	Description of Changes	Approved By
V 1.0	01/02/2025	Initial Release	[Name]