Operation and Maintenance of Tablet Polishing Machine

1) Purpose

The purpose of this SOP is to outline the procedures for operating and maintaining the tablet polishing machine to ensure smooth and polished tablet surfaces.

2) Scope

This SOP applies to all personnel involved in the operation, cleaning, and maintenance of the tablet polishing machine in the manufacturing facility.

3) Responsibilities

It is the responsibility of production operators, maintenance staff, and quality control personnel to follow this SOP to ensure proper operation and maintenance of the tablet polishing machine.

4) Procedure

4.1 Preparation

1. Ensure the work area and equipment are clean and sanitized before starting the polishing process.
2. Verify the availability and integrity of tablets ready for polishing.
3. Inspect the tablet polishing machine, including polishing drums and brushes, to ensure they are clean and in good condition.

4.2 Polishing Process

1. Set up the polishing parameters such as polishing speed, pressure, and duration according to tablet specifications.
2. Load the tablets into the polishing drums and start the polishing process.
3. Monitor the polishing process to ensure uniform and polished surfaces of tablets.

4.3 Cleaning and Maintenance

1. Stop the polishing machine after completing the polishing batch.
2. Remove tablets from the polishing drums and clean the drums and brushes thoroughly to remove any polishing residues.
3. Perform preventive maintenance tasks such as checking brushes, inspecting belts, and lubricating moving parts.

5) Abbreviations, if any

N/A

6) Documents, if any

Batch production record, Cleaning log, Tablet polishing machine specifications

7) Reference, if any

GMP guidelines, Manufacturer’s operating manual for tablet polishing machine

8) SOP Version

Version 1.0