Standard Operating Procedure for Use of Propellants in Aerosol Production
1) Purpose
The purpose of this SOP is to outline procedures for handling and using propellants in aerosol production processes. Proper handling ensures safety, quality, and regulatory compliance throughout the manufacturing process.
2) Scope
This SOP applies to the use of propellants in aerosol production activities conducted at [Company Name], including receiving, storage, handling, and dispensing of propellants.
3) Responsibilities
Production Technicians: Responsible for propellant handling and dispensing.
Quality Control (QC) Personnel: Monitor propellant usage and compliance.
Health and Safety Officers: Ensure adherence to safety protocols.
Facility Manager: Oversee propellant storage and maintenance.
4) Procedure
4.1 Propellant Handling:
4.1.1 Receive propellants from approved suppliers and verify documentation.
4.1.2 Store propellants in designated areas with proper ventilation and fire safety measures.
4.2 Dispensing and Use:
4.2.1 Transfer propellants to production areas using approved dispensing equipment.
4.2.2 Follow specified procedures for measuring and dispensing propellants into aerosol formulations.
4.3 Safety Precautions:
4.3.1 Wear appropriate personal protective equipment (PPE) during propellant handling.
4.3.2 Implement grounding and bonding procedures to prevent static electricity hazards.
4.4 Quality Checks:
4.4.1 Perform visual inspections of propellant containers for integrity and labeling.
4.4.2 Conduct in-process checks to ensure correct propellant quantities and
4.5 Emergency Procedures:
4.5.1 Train personnel on emergency response procedures for propellant spills or leaks.
4.5.2 Maintain emergency response kits and contacts for quick mitigation of incidents.
4.6 Waste Management:
4.6.1 Dispose of empty propellant containers and waste materials according to hazardous waste disposal regulations.
4.6.2 Document disposal activities and maintain records for regulatory compliance.
5) Abbreviations, if any
SOP: Standard Operating Procedure
QC: Quality Control
PPE: Personal Protective Equipment
6) Documents, if any
Propellant Handling Procedures
Safety Data Sheets (SDS) for Propellants
Incident Reports (if applicable)
7) Reference, if any
GMP Guidelines
OSHA Regulations
Local Fire Safety Codes
8) SOP Version
Version 1.0
