Tag: Self-emulsifying drug delivery systems (SEDDS)

SOP for Use of Cryoprotectants in Liposome Formulations Use of Cryoprotectants in Liposome Formulations 1) Purpose The purpose of this SOP is to describe the procedure for incorporating cryoprotectants in liposome formulations to enhance the stability of liposomes during freezing and freeze-drying processes. Cryoprotectants help prevent the fusion, leakage, and destabilization of liposomes, which is…

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SOP for Preparation of Nanoliposomes for Drug Delivery Preparation of Nanoliposomes for Drug Delivery 1) Purpose This SOP outlines the procedure for preparing nanoliposomes for drug delivery applications. Nanoliposomes are nanoscale lipid-based vesicles that encapsulate drugs, improving their bioavailability and targeted delivery. This technique is critical for developing advanced drug formulations with enhanced stability, controlled…

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SOP for Preparation of Liposomes using High-Pressure Homogenization Preparation of Liposomes using High-Pressure Homogenization 1) Purpose The purpose of this SOP is to describe the procedure for preparing liposomes using high-pressure homogenization. This technique applies high shear forces to lipid suspensions to reduce particle size and create uniform, small liposomes suitable for drug delivery and…

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SOP for Sonication Technique for Liposome Size Reduction Sonication Technique for Liposome Size Reduction 1) Purpose The purpose of this SOP is to outline the procedure for using the sonication technique to reduce the size of liposomes. Sonication is a method that applies ultrasonic waves to break down larger multilamellar vesicles (MLVs) into smaller unilamellar…

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SOP for Preparation of Liposomes using Extrusion Method Preparation of Liposomes using Extrusion Method 1) Purpose This SOP describes the preparation of liposomes using the extrusion method. The extrusion technique is used to reduce liposome size and achieve uniform size distribution. Liposomes are passed through membrane filters under pressure, resulting in small unilamellar vesicles (SUVs)…

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SOP for Microfluidization Technique for Liposome Preparation Microfluidization Technique for Liposome Preparation 1) Purpose The purpose of this SOP is to provide step-by-step instructions for the preparation of liposomes using the microfluidization technique. Microfluidization is a high-shear method used to reduce the size of liposomes and achieve uniformity in size. It is an efficient technique…

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SOP for Reverse Phase Evaporation Method for Liposome Preparation Reverse Phase Evaporation Method for Liposome Preparation 1) Purpose The purpose of this SOP is to describe the detailed steps involved in the reverse phase evaporation method (REV) for preparing liposomes. This technique allows for high encapsulation efficiency of hydrophilic drugs by forming water-in-oil emulsions and…

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SOP for Solvent Evaporation Method for Liposome Preparation Solvent Evaporation Method for Liposome Preparation 1) Purpose The purpose of this SOP is to describe the step-by-step procedure for preparing liposomes using the solvent evaporation method. This technique involves dissolving lipids in organic solvents, evaporating the solvent to form a lipid film, and hydrating the lipid…

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SOP for Thin-Film Hydration Method for Liposome Preparation Thin-Film Hydration Method for Liposome Preparation 1) Purpose The purpose of this SOP is to outline the step-by-step procedure for preparing liposomes using the thin-film hydration method. This method involves dissolving lipids in an organic solvent, creating a thin lipid film by solvent evaporation, and hydrating the…

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SOP for Use of Cholesterol in Liposome Formulations Use of Cholesterol in Liposome Formulations 1) Purpose This SOP outlines the process for incorporating cholesterol into liposome formulations. Cholesterol is a critical component used to modulate the fluidity and stability of liposomal membranes. Proper incorporation of cholesterol into liposome formulations ensures that liposomes maintain their structural…

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