Tag: SOP for Pharmacokinetics

SOP for Preparing Target Binding Affinity Reports

SOP for Preparing Target Binding Affinity Reports Standard Operating Procedure (SOP) for Preparing Target Binding Affinity Reports 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to define the process of preparing binding affinity reports for drug discovery studies. Binding affinity reports provide critical information on the strength and specificity of interactions between…

Drug Discovery

SOP for Molecular Dynamics Simulations

SOP for Molecular Dynamics Simulations Standard Operating Procedure (SOP) for Molecular Dynamics Simulations 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the procedure for performing Molecular Dynamics (MD) simulations in drug discovery. MD simulations provide a detailed, time-resolved view of molecular motion, helping to understand protein-ligand interactions, stability, conformational changes,…

Drug Discovery

SOP for Cryo-EM Studies in Drug Development

SOP for Cryo-EM Studies in Drug Development Standard Operating Procedure (SOP) for Cryo-EM Studies in Drug Development 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using Cryo-Electron Microscopy (Cryo-EM) for studying biomolecular structures in drug development. Cryo-EM is a powerful technique for determining the three-dimensional structures of…

Drug Discovery

SOP for NMR Spectroscopy for Structure Elucidation

SOP for NMR Spectroscopy for Structure Elucidation Standard Operating Procedure (SOP) for NMR Spectroscopy for Structure Elucidation 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using Nuclear Magnetic Resonance (NMR) spectroscopy to determine the three-dimensional structure of biomolecules and drug candidates in solution. NMR spectroscopy is a…

Drug Discovery

SOP for X-Ray Crystallography in Drug Discovery

SOP for X-Ray Crystallography in Drug Discovery Standard Operating Procedure (SOP) for X-Ray Crystallography in Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using X-ray crystallography for determining the three-dimensional structure of biomolecules, such as proteins, nucleic acids, and their complexes with drug candidates. X-ray…

Drug Discovery

SOP for Protein Purification for Structural Studies

SOP for Protein Purification for Structural Studies Standard Operating Procedure (SOP) for Protein Purification for Structural Studies 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the process of purifying proteins for structural studies in drug discovery. Protein purification is a critical step in the study of biomolecular structures and interactions,…

Drug Discovery

SOP for Differential Scanning Calorimetry (DSC) in Drug Discovery

SOP for Differential Scanning Calorimetry (DSC) in Drug Discovery Standard Operating Procedure (SOP) for Differential Scanning Calorimetry (DSC) in Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the use of Differential Scanning Calorimetry (DSC) for studying the thermal properties of drug candidates and their interactions with biological macromolecules….

Drug Discovery

SOP for Isothermal Titration Calorimetry (ITC) Studies

SOP for Isothermal Titration Calorimetry (ITC) Studies Standard Operating Procedure (SOP) for Isothermal Titration Calorimetry (ITC) Studies 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using Isothermal Titration Calorimetry (ITC) for studying molecular interactions in drug discovery. ITC is a powerful technique used to directly measure the…

Drug Discovery

SOP for Surface Plasmon Resonance (SPR) Studies

SOP for Surface Plasmon Resonance (SPR) Studies Standard Operating Procedure (SOP) for Surface Plasmon Resonance (SPR) Studies 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the use of Surface Plasmon Resonance (SPR) for studying molecular interactions in drug discovery. SPR is a highly sensitive technique used to measure real-time binding…

Drug Discovery

SOP for Biophysical Methods in Drug Discovery

SOP for Biophysical Methods in Drug Discovery Standard Operating Procedure (SOP) for Biophysical Methods in Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the use of biophysical methods in drug discovery. Biophysical techniques are essential tools for understanding the interaction between drug candidates and biological targets, providing crucial…

Drug Discovery