The Ultimate Resource for Pharmaceutical SOPs and Best Practices
SOP for ADME Screening in Early Drug Discovery Standard Operating Procedure (SOP) for ADME Screening in Early Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the process for conducting ADME (Absorption, Distribution, Metabolism, and Excretion) screening during the early stages of drug discovery. ADME screening is crucial for…
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SOP for Pharmacophore Modeling Standard Operating Procedure (SOP) for Pharmacophore Modeling 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of pharmacophore modeling in drug discovery. Pharmacophore modeling is a computational technique used to identify the essential chemical features required for a molecule to interact with a specific biological…
SOP for Selection of Molecular Scaffolds Standard Operating Procedure (SOP) for Selection of Molecular Scaffolds 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of selecting molecular scaffolds in drug discovery. Molecular scaffolds serve as the core structure of drug molecules and are critical in the design of novel…
SOP for Lead Optimization in Drug Discovery Standard Operating Procedure (SOP) for Lead Optimization in Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of lead optimization in drug discovery. Lead optimization is the phase in drug development where the chemical structure of lead compounds is modified…
SOP for Hit Identification and Prioritization Standard Operating Procedure (SOP) for Hit Identification and Prioritization 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process for identifying and prioritizing hits during the drug discovery process. Hit identification is a critical step where compounds that exhibit desired biological activity against a…
SOP for Compound Library Preparation and Maintenance Standard Operating Procedure (SOP) for Compound Library Preparation and Maintenance 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the process for preparing and maintaining compound libraries used in drug discovery. Compound libraries are essential resources for screening and identifying potential drug candidates. This…
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SOP for Structure-Based Drug Design (SBDD) Standard Operating Procedure (SOP) for Structure-Based Drug Design (SBDD) 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of applying Structure-Based Drug Design (SBDD) in drug discovery. SBDD is a computational method that uses the 3D structure of a target protein or nucleic…
SOP for Fragment-Based Drug Design (FBDD) Standard Operating Procedure (SOP) for Fragment-Based Drug Design (FBDD) 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of applying Fragment-Based Drug Design (FBDD) in drug discovery. FBDD is a computational and experimental approach used to identify small molecule fragments that can bind…
SOP for QSAR Modeling in Drug Discovery Standard Operating Procedure (SOP) for QSAR Modeling in Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of applying Quantitative Structure-Activity Relationship (QSAR) modeling in drug discovery. QSAR modeling is a computational method used to predict the biological activity of…
SOP for In Silico Docking Studies Standard Operating Procedure (SOP) for In Silico Docking Studies 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process for conducting in silico docking studies in drug discovery. In silico docking is a computational technique used to predict the binding interactions between small molecules…